MD83 flight crew reported encountering loss of pressurization in cruise.

Attributes
ACN	1633768
Time
Date	201904
Local Time Of Day	0001-0600
Place
Locale Reference	ZZZ.Airport
State Reference	US
Environment
Flight Conditions	IMC
Aircraft 1
Make Model Name	MD-83
Operating Under FAR Part	Part 121
Flight Phase	Cruise
Flight Plan	IFR
Component
Aircraft Component	Pressurization System
Person 1
Function	First Officer Pilot Not Flying
Qualification	Flight Crew Air Transport Pilot (ATP) Flight Crew Multiengine Flight Crew Instrument
Person 2
Function	Pilot Flying Captain
Qualification	Flight Crew Instrument Flight Crew Air Transport Pilot (ATP) Flight Crew Multiengine
Experience	Flight Crew Total 22500
Events
Anomaly	Aircraft Equipment Problem Critical Inflight Event / Encounter Other / Unknown

Narrative:

While in cruise flight at FL280; the eoap (electronic overhead annuciator panel) 'pressurization flow' light illuminated. We noted the cabin climbing at a rate of 500-1000 fpm. We completed the QRH procedure with no change to the issue. We [notified ATC] and descended immediately to 10;000 ft. At no point did the cabin altitude exceed 7;000 ft. Upon reaching lower altitudes the annunciator light extinguished and the rest of the flight was normal. At the time of the mechanical issue; we were in IMC. Engine and airfoil anti-icing was on.

Original NASA ASRS Text

Title: MD83 Flight crew reported encountering loss of pressurization in cruise.

Narrative: While in cruise flight at FL280; the EOAP (Electronic Overhead Annuciator Panel) 'Pressurization flow' light illuminated. We noted the cabin climbing at a rate of 500-1000 fpm. We completed the QRH procedure with no change to the issue. We [notified ATC] and descended immediately to 10;000 ft. At no point did the cabin altitude exceed 7;000 ft. Upon reaching lower altitudes the annunciator light extinguished and the rest of the flight was normal. At the time of the mechanical issue; we were in IMC. Engine and airfoil anti-icing was on.

Data retrieved from NASA's ASRS site and automatically converted to unabbreviated mixed upper/lowercase text. This report is for informational purposes with no guarantee of accuracy. See NASA's ASRS site for official report.