Narrative:

Aircraft had an MEL for engine bleed on the number 1 engine. Icing conditions were not forecasted. At FL210; 300KTS; ice condition and stall prot ice messages illuminated followed by the automatic opening of the wing anti-ice valves. Shortly after; the bleed 2 leak message illuminated. I continued as the pilot flying and the captain went through the QRH procedure for bleed 2 leak. Additionally; FL230 was requested in order to remain above the cloud layer. Following this; the a-i wing fail message illuminated and the captain accomplished the associated QRH procedure. At this time; with bleed 1 inop due to the MEL; and bleed 2 off due to the QRH procedure for the leak; the cabin altitude hi message illuminated. Oxygen masks were immediately donned; and a descent was initiated. The captain [requested priority handling] with ATC and we descended to 7000. No icing was encountered during the descent and the cabin altitude had not gotten high enough to deploy the passenger oxygen masks. A normal approach and landing were accomplished.

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Original NASA ASRS Text

Title: EMB-190 pilot flying reported a loss of pressurization and immediate descent.

Narrative: Aircraft had an MEL for ENGINE BLEED on the number 1 engine. Icing conditions were not forecasted. At FL210; 300KTS; ICE CONDITION and STALL PROT ICE messages illuminated followed by the automatic opening of the wing anti-ice valves. Shortly after; the BLEED 2 LEAK message illuminated. I continued as the pilot flying and the Captain went through the QRH procedure for BLEED 2 LEAK. Additionally; FL230 was requested in order to remain above the cloud layer. Following this; the A-I WING FAIL message illuminated and the Captain accomplished the associated QRH procedure. At this time; with BLEED 1 inop due to the MEL; and BLEED 2 off due to the QRH procedure for the leak; the CABIN ALT HI message illuminated. Oxygen masks were immediately donned; and a descent was initiated. The Captain [requested priority handling] with ATC and we descended to 7000. No icing was encountered during the descent and the cabin altitude had not gotten high enough to deploy the passenger oxygen masks. A normal approach and landing were accomplished.

Data retrieved from NASA's ASRS site and automatically converted to unabbreviated mixed upper/lowercase text. This report is for informational purposes with no guarantee of accuracy. See NASA's ASRS site for official report.