Narrative:

While cruising at FL360 enroute we received a cabin altitude warning and noted the cabin altitude climbing past 10;000 ft. I was the pilot flying at the time of the warning. The captain and I donned our oxygen masks and the captain took control of the aircraft to start a descent. I took control of the radios and advised [center] that we were descending out of FL360 to 10;000 ft with a cabin pressurization problem. During the descent the cabin pressure slowly decreased below 10;000 ft and eventually stabilized at approximately 1;000 ft as we leveled at 12;000 ft (assigned altitude from ARTCC). We completed the cabin altitude and emergency descent checklists during the descent and [advised ATC]. The captain sent an ACARS message to the company and provided ARTCC with a phone number to call to get hazardous cargo information. We continued the flight at 12;000 ft and landed without issue.after landing; maintenance informed us the cac (center accessory compartment) door was not fully seated and the door seal was protruding from the door. They believed this to be the cause of the pressurization loss.

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Original NASA ASRS Text

Title: MD-11 flight crew reported a loss of pressurization at cruise altitude that resulted in a descent to 12;000 feet.

Narrative: While cruising at FL360 enroute we received a Cabin Altitude warning and noted the cabin altitude climbing past 10;000 ft. I was the pilot flying at the time of the warning. The Captain and I donned our oxygen masks and the Captain took control of the aircraft to start a descent. I took control of the radios and advised [Center] that we were descending out of FL360 to 10;000 ft with a cabin pressurization problem. During the descent the cabin pressure slowly decreased below 10;000 ft and eventually stabilized at approximately 1;000 ft as we leveled at 12;000 ft (assigned altitude from ARTCC). We completed the Cabin Altitude and Emergency Descent checklists during the descent and [advised ATC]. The Captain sent an ACARS message to the company and provided ARTCC with a phone number to call to get hazardous cargo information. We continued the flight at 12;000 ft and landed without issue.After landing; maintenance informed us the CAC (Center Accessory Compartment) door was not fully seated and the door seal was protruding from the door. They believed this to be the cause of the pressurization loss.

Data retrieved from NASA's ASRS site and automatically converted to unabbreviated mixed upper/lowercase text. This report is for informational purposes with no guarantee of accuracy. See NASA's ASRS site for official report.