Narrative:

After departing ZZZ we received an ATC clearance to proceed direct to zzzzz. After referencing the FMC I replied that zzzzz was not on our flight plan and that we where routed rzzz after ZZZZZ1. ATC then asked to verify our routing after ZZZZZ1; this is where we discovered what we had loaded into the FMC; and our jepp app was different than our ATC clearance. We worked out routing with ATC and proceeded to ZZZ1.waiting for the aircraft to arrive late in ZZZ the captain called dispatch to discuss a northerly routing they had us planned for that appeared to take us closer to some weather than our more normal routes. The dispatcher agreed and it was decided to change the route. The amendment came through and reflected the new routing. Once on the aircraft the route that uplinked to the FMC was the new routing as well.relevant factors include first and foremost time compression from the late inbound aircraft exacerbated by slow deplaning and mechanics in the flight deck; a nonstandard gate that required a lengthy walk to and from ops for paperwork as well and 6 mels one of which was added at the last minute. Additionally; it's rare to get a pre departure clearance clearance furthermore the format has changed since it was the norm; this coupled with expectation bias resulted in misreading the pre departure clearance. The departure and first few fixes of the pre departure clearance were exactly the same as our 'new' routing additionally a line under the route titled 'revised segment' stated none. All combined with covid and the fact we are not flying as much as we used to.in this case it had been in excess of an hour and a half since the captain had called dispatch and discussed the route change to when we departed. Along with the time compression; multiple amendments and mels I had forgotten about the route change until we were airborne talking to ATC. In the future whenever there is a route change initiated by the flight crew and or dispatch; I will be sure to mention it as a threat during the departure briefing in an effort to promote a more rigorous scrutinizing of the clearance; flight plan and loaded route.

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Original NASA ASRS Text

Title: Air carrier flight crew reported during climbout they received a route change that was not on the filed route.

Narrative: After departing ZZZ we received an ATC clearance to proceed direct to ZZZZZ. After referencing the FMC I replied that ZZZZZ was not on our flight plan and that we where routed RZZZ after ZZZZZ1. ATC then asked to verify our routing after ZZZZZ1; this is where we discovered what we had loaded into the FMC; and our Jepp app was different than our ATC clearance. We worked out routing with ATC and proceeded to ZZZ1.Waiting for the aircraft to arrive late in ZZZ the Captain called Dispatch to discuss a northerly routing they had us planned for that appeared to take us closer to some weather than our more normal routes. The Dispatcher agreed and it was decided to change the route. The amendment came through and reflected the new routing. Once on the aircraft the route that uplinked to the FMC was the new routing as well.Relevant factors include first and foremost time compression from the late inbound aircraft exacerbated by slow deplaning and mechanics in the flight deck; a nonstandard gate that required a lengthy walk to and from ops for paperwork as well and 6 MELs one of which was added at the last minute. Additionally; it's rare to get a PDC clearance furthermore the format has changed since it was the norm; this coupled with expectation bias resulted in misreading the PDC. The departure and first few fixes of the PDC were exactly the same as our 'new' routing additionally a line under the route titled 'REVISED SEGMENT' stated NONE. All combined with COVID and the fact we are not flying as much as we used to.In this case it had been in excess of an hour and a half since the Captain had called Dispatch and discussed the route change to when we departed. Along with the time compression; multiple amendments and MELs I had forgotten about the route change until we were airborne talking to ATC. In the future whenever there is a route change initiated by the flight crew and or Dispatch; I will be sure to mention it as a threat during the departure briefing in an effort to promote a more rigorous scrutinizing of the clearance; flight plan and loaded route.

Data retrieved from NASA's ASRS site and automatically converted to unabbreviated mixed upper/lowercase text. This report is for informational purposes with no guarantee of accuracy. See NASA's ASRS site for official report.