Narrative:

After leveling at our cruising altitude of FL370 we received a cabin altitude warning. The cabin altitude indicator was showing approximately 10500 ft. We verified proper operation of bleeds and packs and received an EICAS status message; automatic controller 1 and 2 inoperative. We switched to manual control and still were unable to control the cabin altitude. We declared an emergency and followed our procedures for emergency descent to 10000 ft. Returned to ZZZZ and performed an overweight landing. The cabin altitude reached approximately 12000 ft and during the descent the cabin began descending at approximately FL250. No injuries to passenger or crew members. Landing was uneventful.

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Original NASA ASRS Text

Title: B757 FLT CREW HAS LOSS OF CABIN PRESSURIZATION DURING CRUISE; ACCOMPLISHES EMER DSCNT; DECLARES AN EMER AND RETURNS TO DEP ARPT.

Narrative: AFTER LEVELING AT OUR CRUISING ALT OF FL370 WE RECEIVED A CABIN ALT WARNING. THE CABIN ALT INDICATOR WAS SHOWING APPROX 10500 FT. WE VERIFIED PROPER OP OF BLEEDS AND PACKS AND RECEIVED AN EICAS STATUS MESSAGE; AUTO CTLR 1 AND 2 INOP. WE SWITCHED TO MANUAL CTL AND STILL WERE UNABLE TO CTL THE CABIN ALT. WE DECLARED AN EMER AND FOLLOWED OUR PROCS FOR EMER DSCNT TO 10000 FT. RETURNED TO ZZZZ AND PERFORMED AN OVERWT LNDG. THE CABIN ALT REACHED APPROX 12000 FT AND DURING THE DSCNT THE CABIN BEGAN DSNDING AT APPROX FL250. NO INJURIES TO PAX OR CREW MEMBERS. LNDG WAS UNEVENTFUL.

Data retrieved from NASA's ASRS site as of January 2009 and automatically converted to unabbreviated mixed upper/lowercase text. This report is for informational purposes with no guarantee of accuracy. See NASA's ASRS site for official report.